P53S (p.Pro53Ser) variant of AGL (Glycogen debranching enzyme)
P53S (p.Pro53Ser) in AGL (Glycogen debranching enzyme) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes structural context.
P53S (p.Pro53Ser) variant details
- p.Pro53Ser
- NCI-TCGA Cosmic COSV5406
- cosmic curated COSV54060
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.145
- REVEL 0.02
- ESM-1b 0.00
- AlphaMissense 0.08
- MetaLR 0.02
- MetaSVM -1.03
- CADD 17.59
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available