V77L (p.Val77Leu) variant of ADH1B (P00325)
V77L (p.Val77Leu) in ADH1B (P00325) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
V77L (p.Val77Leu) variant details
- p.Val77Leu
- ExAC rs754035032
- TOPMed rs754035032
- gnomAD rs754035032
- Missense
- Variant Prioritization Score for Impact Estimate 0.0813
- REVEL 0.10
- CADD 1.42
- PolyPhen-2 0.00
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available