T128I (p.Thr128Ile) variant of ADH1B (P00325)
T128I (p.Thr128Ile) in ADH1B (P00325) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
T128I (p.Thr128Ile) variant details
- p.Thr128Ile
- TOPMed rs951297322
- gnomAD rs951297322
- Missense
- Variant Prioritization Score for Impact Estimate 0.336
- REVEL 0.23
- CADD 25.00
- PolyPhen-2 0.93
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available