L15P (p.Leu15Pro) variant of ADH1B (P00325)
L15P (p.Leu15Pro) in ADH1B (P00325) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
L15P (p.Leu15Pro) variant details
- p.Leu15Pro
- ExAC rs778345918
- TOPMed rs778345918
- gnomAD rs778345918
- Missense
- Variant Prioritization Score for Impact Estimate 0.397
- REVEL 0.25
- CADD 22.80
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available