K33E (p.Lys33Glu) variant of ADH1B (P00325)
K33E (p.Lys33Glu) in ADH1B (P00325) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
K33E (p.Lys33Glu) variant details
- p.Lys33Glu
- gnomAD rs1217364029
- Missense
- Variant Prioritization Score for Impact Estimate 0.337
- REVEL 0.14
- CADD 23.70
- PolyPhen-2 0.86
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available