K105E (p.Lys105Glu) variant of ADH1B (P00325)
K105E (p.Lys105Glu) in ADH1B (P00325) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
K105E (p.Lys105Glu) variant details
- p.Lys105Glu
- gnomAD rs1168808338
- Missense
- Variant Prioritization Score for Impact Estimate 0.191
- REVEL 0.08
- CADD 15.10
- PolyPhen-2 0.02
- SIFT 0.29
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available