I73M (p.Ile73Met) variant of ADH1B (P00325)
I73M (p.Ile73Met) in ADH1B (P00325) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
I73M (p.Ile73Met) variant details
- p.Ile73Met
- gnomAD rs866353784
- Missense
- Variant Prioritization Score for Impact Estimate 0.182
- REVEL 0.17
- CADD 16.30
- PolyPhen-2 0.95
- SIFT 0.02
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available