G80R (p.Gly80Arg) variant of ADH1B (P00325)
G80R (p.Gly80Arg) in ADH1B (P00325) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
G80R (p.Gly80Arg) variant details
- p.Gly80Arg
- gnomAD rs1260254304
- Missense
- Variant Prioritization Score for Impact Estimate 0.352
- REVEL 0.23
- CADD 23.70
- PolyPhen-2 0.16
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available