G118D (p.Gly118Asp) variant of ADH1B (P00325)
G118D (p.Gly118Asp) in ADH1B (P00325) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
G118D (p.Gly118Asp) variant details
- p.Gly118Asp
- NCI-TCGA Cosmic COSV5929
- cosmic curated COSV59297
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.0476
- REVEL 0.04
- CADD 0.01
- PolyPhen-2 0.00
- SIFT 0.18
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available