F22L (p.Phe22Leu) variant of ADH1B (P00325)
F22L (p.Phe22Leu) in ADH1B (P00325) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
F22L (p.Phe22Leu) variant details
- p.Phe22Leu
- TOPMed rs1733951812
- gnomAD rs1733951812
- Missense
- Variant Prioritization Score for Impact Estimate 0.162
- REVEL 0.07
- CADD 12.20
- PolyPhen-2 0.11
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available