E25A (p.Glu25Ala) variant of ADH1B (P00325)
E25A (p.Glu25Ala) in ADH1B (P00325) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
E25A (p.Glu25Ala) variant details
- p.Glu25Ala
- ExAC rs767328444
- TOPMed rs767328444
- gnomAD rs767328444
- Missense
- Variant Prioritization Score for Impact Estimate 0.394
- REVEL 0.23
- CADD 25.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available