C98Y (p.Cys98Tyr) variant of ADH1B (P00325)
C98Y (p.Cys98Tyr) in ADH1B (P00325) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
C98Y (p.Cys98Tyr) variant details
- p.Cys98Tyr
- ExAC rs760362364
- TOPMed rs760362364
- gnomAD rs760362364
- Missense
- Variant Prioritization Score for Impact Estimate 0.621
- REVEL 0.55
- CADD 26.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 0.00041)
- Structural context available