C98R (p.Cys98Arg) variant of ADH1B (P00325)
C98R (p.Cys98Arg) in ADH1B (P00325) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
C98R (p.Cys98Arg) variant details
- p.Cys98Arg
- ExAC rs770585785
- TOPMed rs770585785
- gnomAD rs770585785
- Missense
- Variant Prioritization Score for Impact Estimate 0.643
- REVEL 0.67
- CADD 27.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available