V28A (p.Val28Ala) variant of ADD1 (Alpha-adducin)
V28A (p.Val28Ala) in ADD1 (Alpha-adducin) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes structural context.
V28A (p.Val28Ala) variant details
- p.Val28Ala
- NCI-TCGA Cosmic COSV5326
- cosmic curated COSV53266
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.356
- REVEL 0.24
- ESM-1b 1.00
- AlphaMissense 0.82
- MetaLR 0.10
- MetaSVM -1.05
- CADD 24.20
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available