T11I (p.Thr11Ile) variant of ADD1 (Alpha-adducin)
T11I (p.Thr11Ile) in ADD1 (Alpha-adducin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data, published literature, and structural context.
T11I (p.Thr11Ile) variant details
- p.Thr11Ile
- gnomAD 4-2875947-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.534
- REVEL 0.36
- ESM-1b 1.00
- AlphaMissense 0.44
- MetaLR 0.22
- MetaSVM -0.65
- CADD 26.90
- Population evidence available
- Structural context available
- Literature evidence available