P65H (p.Pro65His) variant of ADD1 (Alpha-adducin)
P65H (p.Pro65His) in ADD1 (Alpha-adducin) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes structural context.
P65H (p.Pro65His) variant details
- p.Pro65His
- NCI-TCGA Cosmic COSV9929
- cosmic curated COSV99296
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.521
- REVEL 0.44
- ESM-1b 1.00
- AlphaMissense 0.82
- MetaLR 0.23
- MetaSVM -0.62
- CADD 29.20
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available