P43S (p.Pro43Ser) variant of ADD1 (Alpha-adducin)
P43S (p.Pro43Ser) in ADD1 (Alpha-adducin) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes structural context.
P43S (p.Pro43Ser) variant details
- p.Pro43Ser
- NCI-TCGA Cosmic COSV9929
- cosmic curated COSV99296
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.417
- REVEL 0.31
- ESM-1b 1.00
- AlphaMissense 0.90
- MetaLR 0.22
- MetaSVM -0.63
- CADD 26.10
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available