F25L (p.Phe25Leu) variant of ADD1 (Alpha-adducin)
F25L (p.Phe25Leu) in ADD1 (Alpha-adducin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
F25L (p.Phe25Leu) variant details
- p.Phe25Leu
- gnomAD 4-2875988-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.394
- REVEL 0.18
- ESM-1b 1.00
- AlphaMissense 0.99
- MetaLR 0.15
- MetaSVM -0.91
- CADD 25.10
- Population evidence available
- Structural context available
- Literature evidence available