E77G (p.Glu77Gly) variant of ADD1 (Alpha-adducin)
E77G (p.Glu77Gly) in ADD1 (Alpha-adducin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
E77G (p.Glu77Gly) variant details
- p.Glu77Gly
- gnomAD 4-2881932-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.452
- REVEL 0.29
- ESM-1b 1.00
- AlphaMissense 0.45
- MetaLR 0.15
- MetaSVM -0.87
- CADD 25.90
- Population evidence available
- Structural context available
- Literature evidence available