P63S (p.Pro63Ser) variant of ADAMTS13 (Q76LX8)
P63S (p.Pro63Ser) in ADAMTS13 (Q76LX8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
P63S (p.Pro63Ser) variant details
- p.Pro63Ser
- gnomAD rs1554784549
- Missense
- Variant Prioritization Score for Impact Estimate 0.165
- REVEL 0.08
- MetaLR 0.25
- MetaSVM -0.88
- CADD 7.41
- SIFT 0.21
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available