P11L (p.Pro11Leu) variant of ADAMTS13 (Q76LX8)
P11L (p.Pro11Leu) in ADAMTS13 (Q76LX8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
P11L (p.Pro11Leu) variant details
- p.Pro11Leu
- gnomAD 9-133422475-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.14
- REVEL 0.12
- MetaLR 0.33
- MetaSVM -0.78
- CADD 1.48
- PolyPhen-2 0.06
- SIFT 0.24
- Population evidence available
- Structural context available
- Literature evidence available