L13F (p.Leu13Phe) variant of ADAMTS13 (Q76LX8)
L13F (p.Leu13Phe) in ADAMTS13 (Q76LX8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
L13F (p.Leu13Phe) variant details
- p.Leu13Phe
- gnomAD 9-133422480-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.146
- REVEL 0.08
- MetaLR 0.39
- MetaSVM -0.72
- CADD 3.91
- PolyPhen-2 0.00
- SIFT 0.13
- Population evidence available
- Structural context available
- Literature evidence available