F61L (p.Phe61Leu) variant of ADA (Adenosine deaminase)
F61L (p.Phe61Leu) in ADA (Adenosine deaminase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes population frequency data and structural context.
F61L (p.Phe61Leu) variant details
- p.Phe61Leu
- ExAC rs752086551
- gnomAD rs752086551
- Missense
- Variant Prioritization Score for Impact Estimate 0.835
- REVEL 0.89
- CADD 24.10
- PolyPhen-2 0.95
- SIFT 0.18
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available