W163R (p.Trp163Arg) variant of ACE2 (Angiotensin-converting enzyme 2)
W163R (p.Trp163Arg) in ACE2 (Angiotensin-converting enzyme 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
W163R (p.Trp163Arg) variant details
- p.Trp163Arg
- ExAC rs777568369
- TOPMed rs777568369
- Missense
- Variant Prioritization Score for Impact Estimate 0.408
- REVEL 0.28
- CADD 25.40
- PolyPhen-2 0.82
- SIFT 0.04
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available