S2P (p.Ser2Pro) variant of ACE2 (Angiotensin-converting enzyme 2)
S2P (p.Ser2Pro) in ACE2 (Angiotensin-converting enzyme 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
S2P (p.Ser2Pro) variant details
- p.Ser2Pro
- ExAC rs760347219
- gnomAD rs760347219
- Missense
- Variant Prioritization Score for Impact Estimate 0.163
- REVEL 0.07
- CADD 19.30
- PolyPhen-2 0.00
- SIFT 0.03
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available