S128T (p.Ser128Thr) variant of ACE2 (Angiotensin-converting enzyme 2)
S128T (p.Ser128Thr) in ACE2 (Angiotensin-converting enzyme 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
S128T (p.Ser128Thr) variant details
- p.Ser128Thr
- ExAC rs751227277
- gnomAD rs751227277
- Missense
- Variant Prioritization Score for Impact Estimate 0.46
- REVEL 0.37
- CADD 22.90
- PolyPhen-2 0.43
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available