S106L (p.Ser106Leu) variant of ACE2 (Angiotensin-converting enzyme 2)
S106L (p.Ser106Leu) in ACE2 (Angiotensin-converting enzyme 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
S106L (p.Ser106Leu) variant details
- p.Ser106Leu
- TOPMed rs1038445507
- Missense
- Variant Prioritization Score for Impact Estimate 0.297
- REVEL 0.17
- CADD 22.50
- PolyPhen-2 0.10
- SIFT 0.02
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available