S105T (p.Ser105Thr) variant of ACE2 (Angiotensin-converting enzyme 2)
S105T (p.Ser105Thr) in ACE2 (Angiotensin-converting enzyme 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
S105T (p.Ser105Thr) variant details
- p.Ser105Thr
- TOPMed rs1927922165
- Missense
- Variant Prioritization Score for Impact Estimate 0.105
- REVEL 0.04
- CADD 9.71
- PolyPhen-2 0.02
- SIFT 0.32
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available