N58D (p.Asn58Asp) variant of ACE2 (Angiotensin-converting enzyme 2)
N58D (p.Asn58Asp) in ACE2 (Angiotensin-converting enzyme 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
N58D (p.Asn58Asp) variant details
- p.Asn58Asp
- TOPMed rs1222417695
- gnomAD rs1222417695
- Missense
- Variant Prioritization Score for Impact Estimate 0.501
- REVEL 0.45
- CADD 25.90
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available