N159S (p.Asn159Ser) variant of ACE2 (Angiotensin-converting enzyme 2)
N159S (p.Asn159Ser) in ACE2 (Angiotensin-converting enzyme 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
N159S (p.Asn159Ser) variant details
- p.Asn159Ser
- ExAC rs746034076
- TOPMed rs746034076
- gnomAD rs746034076
- Missense
- Variant Prioritization Score for Impact Estimate 0.0521
- REVEL 0.04
- CADD 0.10
- PolyPhen-2 0.00
- SIFT 0.79
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available