N149S (p.Asn149Ser) variant of ACE2 (Angiotensin-converting enzyme 2)
N149S (p.Asn149Ser) in ACE2 (Angiotensin-converting enzyme 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
N149S (p.Asn149Ser) variant details
- p.Asn149Ser
- Ensembl rs373252182
- Missense
- Variant Prioritization Score for Impact Estimate 0.217
- REVEL 0.10
- CADD 14.40
- PolyPhen-2 0.01
- SIFT 0.19
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available