M190T (p.Met190Thr) variant of ACE2 (Angiotensin-converting enzyme 2)
M190T (p.Met190Thr) in ACE2 (Angiotensin-converting enzyme 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
M190T (p.Met190Thr) variant details
- p.Met190Thr
- gnomAD rs976723413
- Missense
- Variant Prioritization Score for Impact Estimate 0.39
- REVEL 0.26
- CADD 24.70
- PolyPhen-2 0.88
- SIFT 0.03
- Most common in the East Asian population (allele frequency 0.00015)
- Structural context available