L9P (p.Leu9Pro) variant of ACE2 (Angiotensin-converting enzyme 2)
L9P (p.Leu9Pro) in ACE2 (Angiotensin-converting enzyme 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
L9P (p.Leu9Pro) variant details
- p.Leu9Pro
- ExAC rs746202722
- TOPMed rs746202722
- gnomAD rs746202722
- Missense
- Variant Prioritization Score for Impact Estimate 0.4
- REVEL 0.28
- CADD 24.60
- PolyPhen-2 0.46
- SIFT 0.01
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available