G173S (p.Gly173Ser) variant of ACE2 (Angiotensin-converting enzyme 2)
G173S (p.Gly173Ser) in ACE2 (Angiotensin-converting enzyme 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
G173S (p.Gly173Ser) variant details
- p.Gly173Ser
- ExAC rs754511501
- gnomAD rs754511501
- Missense
- Variant Prioritization Score for Impact Estimate 0.474
- REVEL 0.30
- CADD 24.80
- PolyPhen-2 0.88
- SIFT 0.01
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available