E197G (p.Glu197Gly) variant of ACE2 (Angiotensin-converting enzyme 2)
E197G (p.Glu197Gly) in ACE2 (Angiotensin-converting enzyme 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
E197G (p.Glu197Gly) variant details
- p.Glu197Gly
- gnomAD rs1271221183
- Missense
- Variant Prioritization Score for Impact Estimate 0.181
- REVEL 0.11
- CADD 17.10
- PolyPhen-2 0.18
- SIFT 0.08
- Most common in the East Asian population (allele frequency 0.00015)
- Structural context available