A80T (p.Ala80Thr) variant of ACE2 (Angiotensin-converting enzyme 2)
A80T (p.Ala80Thr) in ACE2 (Angiotensin-converting enzyme 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
A80T (p.Ala80Thr) variant details
- p.Ala80Thr
- Ensembl rs1927925500
- Missense
- Variant Prioritization Score for Impact Estimate 0.298
- REVEL 0.20
- CADD 18.50
- PolyPhen-2 0.90
- SIFT 0.02
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available