A25V (p.Ala25Val) variant of ACE2 (Angiotensin-converting enzyme 2)
A25V (p.Ala25Val) in ACE2 (Angiotensin-converting enzyme 2) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The record also includes experimental measurements and structural context.
A25V (p.Ala25Val) variant details
- p.Ala25Val
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available
- ACE2 binding to SARS-CoV-2 spike protein, low affinity: score -0.569