P15S (p.Pro15Ser) variant of ACE (Angiotensin-converting enzyme)
P15S (p.Pro15Ser) in ACE (Angiotensin-converting enzyme) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
P15S (p.Pro15Ser) variant details
- p.Pro15Ser
- TOPMed rs1193133040
- gnomAD rs1193133040
- Missense
- Variant Prioritization Score for Impact Estimate 0.122
- REVEL 0.02
- ESM-1b 0.00
- AlphaMissense 0.08
- MetaLR 0.04
- MetaSVM -1.01
- CADD 4.33
- Most common in the HGDP:SAN population (allele frequency 1)
- Structural context available