L21R (p.Leu21Arg) variant of ACE (Angiotensin-converting enzyme)
L21R (p.Leu21Arg) in ACE (Angiotensin-converting enzyme) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes structural context.
L21R (p.Leu21Arg) variant details
- p.Leu21Arg
- TOPMed rs2049629351
- Missense
- Variant Prioritization Score for Impact Estimate 0.246
- REVEL 0.13
- ESM-1b 1.00
- AlphaMissense 0.14
- MetaLR 0.04
- MetaSVM -1.04
- SIFT 0.09
- Structural context available