L21P (p.Leu21Pro) variant of ACE (Angiotensin-converting enzyme)
L21P (p.Leu21Pro) in ACE (Angiotensin-converting enzyme) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
L21P (p.Leu21Pro) variant details
- p.Leu21Pro
- TOPMed rs2049629351
- Missense
- Variant Prioritization Score for Impact Estimate 0.286
- REVEL 0.28
- ESM-1b 0.99
- AlphaMissense 0.10
- MetaLR 0.04
- MetaSVM -1.05
- CADD 15.30
- Population evidence available
- Structural context available