L14P (p.Leu14Pro) variant of ACE (Angiotensin-converting enzyme)
L14P (p.Leu14Pro) in ACE (Angiotensin-converting enzyme) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
L14P (p.Leu14Pro) variant details
- p.Leu14Pro
- TOPMed rs1207951348
- Missense
- Variant Prioritization Score for Impact Estimate 0.131
- REVEL 0.05
- ESM-1b 0.30
- AlphaMissense 0.07
- MetaLR 0.06
- MetaSVM -1.01
- CADD 7.96
- Most common in the HGDP:BOUGAINVILLE population (allele frequency 1)
- Structural context available