G6A (p.Gly6Ala) variant of ACE (Angiotensin-converting enzyme)
G6A (p.Gly6Ala) in ACE (Angiotensin-converting enzyme) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
G6A (p.Gly6Ala) variant details
- p.Gly6Ala
- TOPMed rs1267076673
- gnomAD rs1267076673
- Missense
- Variant Prioritization Score for Impact Estimate 0.198
- REVEL 0.04
- ESM-1b 0.00
- AlphaMissense 0.13
- MetaLR 0.04
- MetaSVM -1.07
- CADD 12.60
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available