G2R (p.Gly2Arg) variant of ACE (Angiotensin-converting enzyme)
G2R (p.Gly2Arg) in ACE (Angiotensin-converting enzyme) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
G2R (p.Gly2Arg) variant details
- p.Gly2Arg
- Ensembl rs2049627089
- Missense
- Variant Prioritization Score for Impact Estimate 0.24
- REVEL 0.09
- ESM-1b 0.00
- AlphaMissense 0.57
- MetaLR 0.11
- MetaSVM -0.82
- CADD 24.90
- Most common in the HGDP:BOUGAINVILLE population (allele frequency 1)
- Structural context available