G11W (p.Gly11Trp) variant of ACE (Angiotensin-converting enzyme)
G11W (p.Gly11Trp) in ACE (Angiotensin-converting enzyme) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
G11W (p.Gly11Trp) variant details
- p.Gly11Trp
- gnomAD 17-63477125-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.199
- REVEL 0.02
- ESM-1b 0.00
- AlphaMissense 0.12
- MetaLR 0.04
- MetaSVM -1.03
- CADD 3.79
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available