G11E (p.Gly11Glu) variant of ACE (Angiotensin-converting enzyme)
G11E (p.Gly11Glu) in ACE (Angiotensin-converting enzyme) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
G11E (p.Gly11Glu) variant details
- p.Gly11Glu
- gnomAD 17-63477126-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.228
- REVEL 0.01
- ESM-1b 0.34
- AlphaMissense 0.11
- MetaLR 0.03
- MetaSVM -1.02
- CADD 4.09
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available
- Literature evidence available