G11G (p.Gly11Gly) variant of ACAT1 (P24752)
G11G (p.Gly11Gly) in ACAT1 (P24752) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
G11G (p.Gly11Gly) variant details
- p.Gly11Gly
- rs761018640
- gnomAD 11-108121639-C-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.219
- AlphaMissense 0.09
- MetaLR 0.14
- MetaSVM -0.93
- CADD 11.50
- PolyPhen-2 0.29
- SIFT 0.10
- Most common in the HGDP:MAKRANI population (allele frequency 0.023)
- Structural context available
- Literature evidence available