T66T (p.Thr66Thr) variant of ACAN (Aggrecan core protein)
T66T (p.Thr66Thr) in ACAN (Aggrecan core protein) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
T66T (p.Thr66Thr) variant details
- p.Thr66Thr
- rs1448004781
- gnomAD 15-88838790-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0831
- CADD 0.34
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available
- Literature evidence available