R77R (p.Arg77Arg) variant of ACAN (Aggrecan core protein)
R77R (p.Arg77Arg) in ACAN (Aggrecan core protein) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
R77R (p.Arg77Arg) variant details
- p.Arg77Arg
- gnomAD 15-88838823-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0953
- CADD 2.07
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available