K74K (p.Lys74Lys) variant of ACAN (Aggrecan core protein)
K74K (p.Lys74Lys) in ACAN (Aggrecan core protein) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
K74K (p.Lys74Lys) variant details
- p.Lys74Lys
- gnomAD 15-88838814-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.299
- CADD 8.84
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available
- Literature evidence available