G36R (p.Gly36Arg) variant of ACADM (P11310)
G36R (p.Gly36Arg) in ACADM (P11310) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
G36R (p.Gly36Arg) variant details
- p.Gly36Arg
- rs774074624
- NCI-TCGA Cosmic COSV1008
- cosmic curated COSV10089
- ExAC rs774074624
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.744
- REVEL 0.71
- CADD 27.90
- PolyPhen-2 0.88
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the South Asian population (allele frequency 7e-05)
- Structural context available